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Break the Cycle of Metabolic Imbalance
and Unwanted Weight Gain

About IGOB131®

IGOB131 is a patented, natural extract of Irvingia gabonensis or African mango that is clinically proven to restore and maintain metabolic balance that is essential for healthy body weight and composition. This traditional medicinal plant has unique bioactive properties that modulate hormones linked to appetite, satiety, insulin sensitivity, and energy metabolism.


Recommended adult daily serving: 300 mgs. Suitable for a wide range of food, beverage and supplement product applications.

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5 Clinical

How IGOB131 Works

Researchers have identified unique bioactive properties that make IGOB131 an effective functional ingredient for weight loss and weight management products. IGOB131 helps achieve healthy levels of:


  • Adiponectin, a hormone fat cells produce to balance energy, reduce fat cell size and protect heart and vascular cells

  • Leptin, a hormone the brain relies upon to help regulate appetite, satiety and fat stores

  • C-reactive protein, a systemic inflammation biomarker

  • Total cholesterol and LDL cholesterol

Clinical Research

Five peer-reviewed, double-blind, placebo-controlled clinical studies with more than 300 subjects consistently showed IGOB131 safely restored metabolic wellness and significantly reduced body weight and improved body composition.


In a randomized, double-blind study of 102 overweight subjects, participants taking 150 mgs of IGOB131 twice daily before meals for 10 weeks had statistically significant improvements in body weight and composition in comparison to the control group. The results, which were published in Lipids in Health and Disease, showed IGOB131 group:


  • Lost an average of 28 lbs.*

  • Cut 6.7 inches from their waistlines*

  • Reduced body fat 18.4%*


In addition, blood serum samples of the IGOB131 group showed significant improvements in cholesterol, LDL cholesterol, blood glucose, C-reactive protein, adiponectin and leptin levels in comparison to the placebo group.*


Similar results were obtained in three additional clinical studies involving an additional 160 subjects.*  IGOB131 is U.S. FDA GRAS and supported by multiple published safety and toxicology studies.

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Source: Lipids in Health and Disease. 2009.

Compelling Product Claims*

The science of IGOB131 supports multiple structure/function claims:

  • Reduces adult-onset weight gain

  • Supports healthy weight management

  • Increases satiety/appetite control

  • Enhances mood, reducing emotional eating

  • Supports cardiovascular health

  • Supports metabolic balance/metabolic wellness


Clinical Studies

Effect of Ellagic Acid on Body Fat and Triglyceride Reduction in Healthy Overweight Volunteers: a Randomized, Double-blind, Placebo-controlled Parallel Group Study. Functional Foods in Health and Disease. 2020. 

The Effect of Extracts of Irvingia gabonensis (IGOB131) and Dichrostachys glomerata (Dyglomera™) on Body Weight and Lipid Parameters of Healthy Overweight Participants. Functional Foods in Health and Disease. 2015.

IGOB131, a Novel Seed Extract of the West African Plant Irvingia gabonensis, Significantly Reduces Body Weight and Improves Metabolic Parameters in Overweight Humans in a Randomized, Double-blind, Placebo-controlled Investigation. Lipids in Health and Disease. 2009.


The Use of a Cissus quadrangularis/Irvingia gabonensis Combination in the Management of Weight Loss: a Double-blind, Placebo-controlled Study.  Lipids in Health and Disease. 2008.


The Effect of Irvingia gabonensis Seeds on Body Weight and Blood Lipids of Obese Subjects in Cameroon. Lipids in Health and Disease. 2005.

Preclinical/Safety-Tox Studies

Subchronic Toxicity and Mutagenicity/Genotoxicity Studies of Irvingia gabonensis Extract (IGOB131). Food and Chemical Toxicology. 2012.

*This website is intended to provide scientific and educational information only. These statements have not been evaluated by the U.S. Food and Drug Administration nor any other regulatory agency in any country. Manufacturers should consult with their legal counsel to confirm the appropriateness of claim language in their respective region.

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