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Naturally Supports Healthy Weight Management, Cardiovascular Health and Metabolic Wellness

About Cissus CQR-300®

CQR-300 is a patented extract of Cissus quadrangularis, an indigenous plant of India, Asia and West Africa long used in traditional medicine. It also contains cholesterol-lowering phytosterols and naturally occurring vitamin C, vitamin A and calcium.


The biologically active components of Cissus quadrangularis support numerous health benefits, including weight loss, heart health and metabolic wellness. Five peer-reviewed, placebo-controlled clinical studies with more than 300 subjects consistently demonstrated that CQR-300 may significantly reduce body weight, percentage body fat and waist and hip circumference in 6 to 8 weeks.


Recommended adult daily serving: 300 mgs. Ideal for capsules, tablets, powdered mixes and beverages, as well as numerous other dietary supplement applications.

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5 Clinical

How Cissus CQR-300 Works

Preclinical research shows that CQR-300 naturally inhibits select enzymes (lipase, a-amylase, a-glucosidase) critical to the digestion and absorption of fat and carbohydrates. Together with a healthy diet and exercise, CQR-300 helps individuals achieve and maintain their body weight goals.

Clinical Research

A randomized, double-blind, placebo-controlled study involving 67 overweight adults ages 25-60 was conducted over eight weeks to evaluate the efficacy of 300mgs of CQR-300 in reducing the percentage of body fat. Multiple baseline and post-study weight and fat measurements were taken, including body imaging with dual-energy X-ray absorption (DEXA), which is considered the gold standard for determining body fat percentages.


After eight weeks, the CQR-300 group:


  • Lost an average of 16.3 pounds, compared with 1.3 pounds for the placebo group.*


  • Reduced body fat 12.8% as measured by DEXA, compared with 0.3% gain in body fat in the placebo group.*


  • Trimmed waist circumference 8.9%, compared with a 1.6% reduction in the control group.*


  • Reduced hip circumference 7.7%, compared with a 1.8% decrease in the placebo group.*


  • Experienced statistically significant improvements in blood pressure, total cholesterol, triglycerides and leptin and adiponectin, two hormones that help regulate satiety, appetite and metabolism.*

Source: Journal of Alternative and Complementary Medicine, 2019

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*This website is intended to provide scientific and educational information only. These statements have not been evaluated by the U.S. Food and Drug Administration nor any other regulatory agency in any country. Manufacturers should consult with their legal counsel to confirm the appropriateness of claim language in their respective region.

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