Beyond GLP-1: The Hormone Trio Driving Smarter Weight Support

GLP-1 may dominate headlines, but it’s not the only hormone that matters for weight and metabolic health. In the latest issue of Vitalstoffe, a leading German trade publication focused on scientifically backed dietary supplement ingredients, Gateway Health Alliances President Shil Kothari highlights the critical roles of adiponectin, leptin, and insulin.

Gateway’s patented African mango extract, IGOB131® (Irvingia gabonensis), has been shown in five clinical studies to modulate these hormones—delivering significant improvements in weight, body composition, cholesterol, blood sugar, and inflammation. With a compact daily dose of just 300 mg, IGOB131® offers a clinically validated, hormone-focused approach to metabolic wellness that complements, rather than competes with, GLP-1 strategies.